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T. divaricata has A variety of 'alkaloid' compounds, the molecules of that have carbon-based frameworks where the atoms are linked into a number of rings.

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At first isolated from the bark of the tropical, ornamental flowering plant Tabernaemontana divaricata

But because conolidine is not really an opioid, it'd supply soreness aid without having complications like the development of dependence and nausea.

"We verified that conolidine binds on the newly discovered opioid receptor ACKR3, whilst demonstrating no affinity for another four classical opioid receptors. By doing so, conolidine blocks ACKR3 and stops it from trapping the Normally secreted opioids, which subsequently improves their availability for interacting with classical receptors.

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